{"id":116,"date":"2020-11-30T10:33:40","date_gmt":"2020-11-30T10:33:40","guid":{"rendered":"http:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/?page_id=116"},"modified":"2026-06-08T13:54:25","modified_gmt":"2026-06-08T13:54:25","slug":"programas-grupos-y-lineas-de-investigacion","status":"publish","type":"page","link":"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/programas-grupos-y-lineas-de-investigacion\/","title":{"rendered":"Programs, groups and lines of research"},"content":{"rendered":"<div class=\"wp-block-stackable-columns alignfull stk-block-columns stk-block stk-49c10bb stk-block-background stk--has-background-overlay\" data-block-id=\"49c10bb\"><style>.stk-49c10bb {background-color:linear-gradient(135deg,rgb(161,9,157) 1%,rgb(63,37,132) 100%) !important;margin-top:-3% !important;margin-bottom:3% !important;}.stk-49c10bb:before{background-image:linear-gradient(135deg,rgb(161,9,157) 1%,rgb(63,37,132) 100%) !important;}.stk-49c10bb-column{justify-content:center !important;}<\/style><div class=\"stk-row stk-inner-blocks stk-block-content stk-content-align stk-49c10bb-column stk--flex alignfull\">\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-429e70e\" data-v=\"4\" data-block-id=\"429e70e\"><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-429e70e-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-429e70e-inner-blocks\">\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-616317e\" id=\"programas-grupos-y-lineas-de-investigacion\" data-block-id=\"616317e\"><style>.stk-616317e {align-items:center !important;display:flex !important;}.stk-616317e .stk-block-heading__text{color:#ffffff !important;font-weight:800 !important;}<\/style><h2 class=\"stk-block-heading__text has-text-color has-text-align-center\">Programs, groups and lines of research<\/h2><\/div>\n<\/div><\/div><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-stackable-columns alignfull stk-block-columns stk-block stk-95b6153\" data-block-id=\"95b6153\"><div class=\"stk-row stk-inner-blocks stk-block-content stk-content-align stk-95b6153-column alignfull\">\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-524e908\" data-v=\"4\" data-block-id=\"524e908\"><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-524e908-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-524e908-inner-blocks\">\n<div class=\"wp-block-stackable-columns alignfull stk-block-columns stk-block stk-bbf3c2f\" data-block-id=\"bbf3c2f\"><style>.stk-bbf3c2f {margin-top:0% !important;margin-right:var(--stk--preset--spacing--60, 2.25rem) !important;margin-bottom:0% !important;margin-left:var(--stk--preset--spacing--60, 2.25rem) !important;}.stk-bbf3c2f-column{--stk-column-gap:var(--stk--preset--spacing--40, 1rem) !important;}@media screen and (max-width: 767px){.stk-bbf3c2f {margin-right:1% !important;margin-left:1% !important;}}<\/style><div class=\"stk-row stk-inner-blocks stk-block-content stk-content-align stk-bbf3c2f-column alignfull\">\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-22a05ac\" data-v=\"4\" data-block-id=\"22a05ac\"><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-22a05ac-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-22a05ac-inner-blocks\">\n<div class=\"wp-block-stackable-text stk-block-text stk-block stk-94a2a0b\" data-block-id=\"94a2a0b\"><style>.stk-94a2a0b {padding-top:3% !important;padding-left:4% !important;}<\/style><p class=\"stk-block-text__text\">The University Institute for Regional Development (IUDR) at the University of La Laguna is a center for research and specialized training. The Institute&#039;s primary objective is to promote an open research platform of the highest academic caliber within the broad framework of its constituent areas of knowledge. Currently, the IUDR includes professors and researchers from the fields of Law, Economics, Statistics, Operations Research and Computer Science, and Geography at the University of La Laguna, and also involves researchers from other national and international institutions and universities.<\/p><\/div>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-f7df150 stk-block-background stk--has-background-overlay\" data-v=\"4\" data-block-id=\"f7df150\"><style>.stk-f7df150 {background-image:url(https:\/\/www.ull.es\/institutos\/instituto-universitario-de-desarrollo-regional\/wp-content\/uploads\/sites\/28\/2022\/04\/desarrollo-3.jpg) !important;}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-f7df150-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-f7df150-inner-blocks\">\n<div class=\"wp-block-stackable-spacer stk-block-spacer stk--no-padding stk-block stk-49de92d\" data-block-id=\"49de92d\"><style>.stk-49de92d {height:350px !important;}<\/style><\/div>\n<\/div><\/div><\/div>\n<\/div><\/div>\n<\/div><\/div><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-stackable-columns stk-block-columns stk-block stk-8b59b96\" data-block-id=\"8b59b96\"><style>.stk-8b59b96 .stk--block-align-8b59b96{align-items:flex-start !important;}.stk-8b59b96 {margin-top:25px !important;}.stk-8b59b96-column{--stk-columns-spacing:0px !important;--stk-column-gap:50px !important;}@media screen and (max-width: 767px){.stk-8b59b96-column{row-gap:var(--stk--preset--spacing--60, 2.25rem) !important;}}<\/style><div class=\"stk-row stk-inner-blocks stk--block-align-8b59b96 stk-block-content stk-content-align stk-8b59b96-column\">\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-dbb7e15\" data-v=\"4\" data-block-id=\"dbb7e15\"><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-dbb7e15-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-dbb7e15-inner-blocks\">\n<details class=\"wp-block-stackable-accordion stk-block-accordion stk-inner-blocks stk-block-content stk-block stk-7c390cd is-style-default\" id=\"enfermedades-de-base-geneticas-y-raras\" data-block-id=\"7c390cd\"><style>.stk-7c390cd {border-style:solid !important;border-top-width:0px !important;border-right-width:0px !important;border-bottom-width:1px !important;border-left-width:0px !important;margin-bottom:11px !important;}<\/style>\n<summary class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-c927805 stk--container-small stk-block-accordion__heading\" data-v=\"4\" data-block-id=\"c927805\"><style>.stk-c927805 {padding-top:2px !important;padding-right:2px !important;padding-bottom:2px !important;padding-left:2px !important;}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-c927805-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-c927805-inner-blocks\">\n<div class=\"wp-block-stackable-icon-label stk-block-icon-label stk-block stk-7935446\" data-block-id=\"7935446\"><style>.stk-7935446 .stk-inner-blocks{gap:39px !important;}@media screen and (max-width: 1023px){.stk-7935446 .stk-inner-blocks{gap:39px !important;}}@media screen and (max-width: 767px){.stk-7935446 .stk-inner-blocks{gap:39px !important;}}<\/style><div class=\"stk-row stk-inner-blocks stk-block-content\">\n<div class=\"wp-block-stackable-icon stk-block-icon stk-block stk-9a468d5\" data-block-id=\"9a468d5\"><style>.stk-9a468d5 .stk--svg-wrapper .stk--inner-svg svg:last-child{height:25px !important;width:25px !important;}.stk-9a468d5 .stk--svg-wrapper .stk--inner-svg svg:last-child, .stk-9a468d5 .stk--svg-wrapper .stk--inner-svg svg:last-child :is(g, path, rect, polygon, ellipse){fill:#5c068c !important;}<\/style><span class=\"stk--svg-wrapper stk--has-icon2\"><div class=\"stk--inner-svg\"><svg style=\"height:0;width:0\"><defs><lineargradient id=\"linear-gradient-9a468d5\" x1=\"0\" x2=\"100%\" y1=\"0\" y2=\"0\"><stop offset=\"0%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-9-a-468-d-5-color-1)\"><\/stop><stop offset=\"100%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-9-a-468-d-5-color-2)\"><\/stop><\/lineargradient><\/defs><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 448 512\" aria-hidden=\"true\" width=\"32\" height=\"32\"><path d=\"M416 0c17.7 0 32 14.3 32 32c0 59.8-30.3 107.5-69.4 146.6c-28 28-62.5 53.5-97.3 77.4l-2.5 1.7c-11.9 8.1-23.8 16.1-35.5 23.9l0 0 0 0 0 0-1.6 1c-6 4-11.9 7.9-17.8 11.9c-20.9 14-40.8 27.7-59.3 41.5H283.3c-9.8-7.4-20.1-14.7-30.7-22.1l7-4.7 3-2c15.1-10.1 30.9-20.6 46.7-31.6c25 18.1 48.9 37.3 69.4 57.7C417.7 372.5 448 420.2 448 480c0 17.7-14.3 32-32 32s-32-14.3-32-32H64c0 17.7-14.3 32-32 32s-32-14.3-32-32c0-59.8 30.3-107.5 69.4-146.6c28-28 62.5-53.5 97.3-77.4c-34.8-23.9-69.3-49.3-97.3-77.4C30.3 139.5 0 91.8 0 32C0 14.3 14.3 0 32 0S64 14.3 64 32H384c0-17.7 14.3-32 32-32zM338.6 384H109.4c-10.1 10.6-18.6 21.3-25.5 32H364.1c-6.8-10.7-15.3-21.4-25.5-32zM109.4 128H338.6c10.1-10.7 18.6-21.3 25.5-32H83.9c6.8 10.7 15.3 21.3 25.5 32zm55.4 48c18.4 13.8 38.4 27.5 59.3 41.5c20.9-14 40.8-27.7 59.3-41.5H164.7z\"\/><\/svg><\/div><div class=\"stk--inner-svg stk--icon-2\" style=\"display:none\"><svg style=\"height:0;width:0\"><defs><lineargradient id=\"linear-gradient-9a468d5\" x1=\"0\" x2=\"100%\" y1=\"0\" y2=\"0\"><stop offset=\"0%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-9-a-468-d-5-color-1)\"><\/stop><stop offset=\"100%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-9-a-468-d-5-color-2)\"><\/stop><\/lineargradient><\/defs><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 512 512\" aria-hidden=\"true\" width=\"32\" height=\"32\"><path d=\"M160 32c0-17.7 14.3-32 32-32h32c17.7 0 32 14.3 32 32c17.7 0 32 14.3 32 32V288c0 17.7-14.3 32-32 32c0 17.7-14.3 32-32 32H192c-17.7 0-32-14.3-32-32c-17.7 0-32-14.3-32-32V64c0-17.7 14.3-32 32-32zM32 448H320c70.7 0 128-57.3 128-128s-57.3-128-128-128V128c106 0 192 86 192 192c0 49.2-18.5 94-48.9 128H480c17.7 0 32 14.3 32 32s-14.3 32-32 32H320 32c-17.7 0-32-14.3-32-32s14.3-32 32-32zm80-64H304c8.8 0 16 7.2 16 16s-7.2 16-16 16H112c-8.8 0-16-7.2-16-16s7.2-16 16-16z\"\/><\/svg><\/div><\/span><\/div>\n\n\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-31863c1\" id=\"acceso\" data-block-id=\"31863c1\"><style>.stk-31863c1 .stk-block-heading__text{color:#000000 !important;font-weight:500 !important;font-family:\"ArgentumSans\", Sans-serif !important;}<\/style><h4 class=\"stk-block-heading__text has-text-color\"><span style=\"color: #000000;\" class=\"stk-highlight\">Genetic and rare diseases<\/span><\/h4><\/div>\n<\/div><\/div>\n<\/div><\/div><\/summary>\n\n\n\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-5222666 stk-block-accordion__content\" data-v=\"4\" data-block-id=\"5222666\"><style>.stk-5222666 {margin-top:-30px !important;}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-5222666-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-5222666-inner-blocks\">\n<ul class=\"wp-block-list\">\n<li>The definition of this program is shaped by the characteristics of the Canary Islands due to their history and geographical location. The current genome of the Canarian population stems from North African aboriginal heritage, which, together with European influence from the 15th century onward, forms a genome unique in the world. Furthermore, many pathologies have a genetic component influenced by the island context, due to the founder effect and the lack of infrastructure that historically fostered inbreeding. The research groups participating in this program are focused on studying the molecular basis of cancer and rare metabolic diseases. In the case of cancer, the objectives of these groups are to advance prevention, diagnosis, the identification of biological causes, and the development of effective treatments, with the aim of transforming this serious health problem into a chronic condition rather than a fatal disorder. Furthermore, although rare diseases affect only a limited population (fewer than 2,000 individuals in Europe), the number of different diseases is very large (more than 5,000), meaning the total number of affected patients could reach over 30 million in the European Union. In the medium and long term, this program aims to develop personalized medicine and strengthen collaborations with industry.<br>List of groups (click to expand information)\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/checkpoint-en-respuesta-a-dano-en-el-dna-y-enfermedades-humanas\/\" target=\"_blank\" rel=\"noreferrer noopener\">Checkpoint in response to DNA damage and human diseases<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/205536\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Veronique Smits<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/estres-replicativo-y-tumorogenesis\/\" target=\"_blank\" rel=\"noreferrer noopener\">Replicative stress and tumorigenesis<\/a>\u00a0(<a href=\"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/estres-replicativo-y-tumorogenesis\/\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Raimundo Freire Betancor<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/portalciencia.ull.es\/grupos\/6393\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Genomics and health<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/82078\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. M\u00aa del Mar del Pino Yanes<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/inestabilidad-genomica-y-cancer\/\" target=\"_blank\" rel=\"noreferrer noopener\">Genomic instability and cancer<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/205539\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. F\u00e9lix Mach\u00edn Concepci\u00f3n<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/patologia-molecular-de-enfermedades-raras-y-metabolicas\/\" target=\"_blank\" rel=\"noreferrer noopener\">Molecular pathology of rare and metabolic diseases<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/81925\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Eduardo Salido Ruiz<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/variacion-genetica-y-enfermedad\/\" target=\"_blank\" rel=\"noreferrer noopener\">Genetic variation and disease<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/205537\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Carlos Flores Infante<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/portalciencia.ull.es\/grupos\/6286\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Developmental Biology<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/81785\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Pablo Mart\u00edn Vasallo<\/a>,\u00a0<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/82364\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Julio T. \u00c1vila Marrero<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/portalciencia.ull.es\/grupos\/6441\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">BioLab \u2013 Early pharmacological profiling of small molecules<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/81195\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Jos\u00e9 M. Padr\u00f3n Carrillo<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/portalciencia.ull.es\/grupos\/24600\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Clinical, genetic and molecular epidemiology (EpiGeM)<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/152401\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Itahisa Marcelino Rodr\u00edguez<\/a>,\u00a0<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/82552\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. V\u00edctor Garc\u00eda Tagua<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/personalizacion-de-tratamientos-oncologicos\/\" target=\"_blank\" rel=\"noreferrer noopener\">Personalization of cancer treatments<\/a>\u00a0(Dr. Fernando Guti\u00e9rrez Nicol\u00e1s)<\/li>\n\n\n\n<li><a href=\"https:\/\/portalciencia.ull.es\/grupos\/199109\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Chromatin Metabolism<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/152341\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Jonay Garc\u00eda Luis<\/a>)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div><\/div><\/div>\n<\/details>\n\n\n\n<details class=\"wp-block-stackable-accordion stk-block-accordion stk-inner-blocks stk-block-content stk-block stk-cbe1751 is-style-default\" id=\"enfermedades-cronicas-relacionadas-con-el-envejecimiento\" data-block-id=\"cbe1751\"><style>.stk-cbe1751 {border-style:solid !important;border-top-width:0px !important;border-right-width:0px !important;border-bottom-width:1px !important;border-left-width:0px !important;margin-bottom:11px !important;}<\/style>\n<summary class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-4b0f8dc stk--container-small stk-block-accordion__heading\" data-v=\"4\" data-block-id=\"4b0f8dc\"><style>.stk-4b0f8dc {padding-top:2px !important;padding-right:2px !important;padding-bottom:2px !important;padding-left:2px !important;}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-4b0f8dc-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-4b0f8dc-inner-blocks\">\n<div class=\"wp-block-stackable-icon-label stk-block-icon-label stk-block stk-5efdb36\" data-block-id=\"5efdb36\"><style>.stk-5efdb36 .stk-inner-blocks{gap:39px !important;}@media screen and (max-width: 1023px){.stk-5efdb36 .stk-inner-blocks{gap:39px !important;}}@media screen and (max-width: 767px){.stk-5efdb36 .stk-inner-blocks{gap:39px !important;}}<\/style><div class=\"stk-row stk-inner-blocks stk-block-content\">\n<div class=\"wp-block-stackable-icon stk-block-icon stk-block stk-725ba41\" data-block-id=\"725ba41\"><style>.stk-725ba41 .stk--svg-wrapper .stk--inner-svg svg:last-child{height:25px !important;width:25px !important;}.stk-725ba41 .stk--svg-wrapper .stk--inner-svg svg:last-child, .stk-725ba41 .stk--svg-wrapper .stk--inner-svg svg:last-child :is(g, path, rect, polygon, ellipse){fill:#5c068c !important;}<\/style><span class=\"stk--svg-wrapper stk--has-icon2\"><div class=\"stk--inner-svg\"><svg style=\"height:0;width:0\"><defs><lineargradient id=\"linear-gradient-725ba41\" x1=\"0\" x2=\"100%\" y1=\"0\" y2=\"0\"><stop offset=\"0%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-725-ba-41-color-1)\"><\/stop><stop offset=\"100%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-725-ba-41-color-2)\"><\/stop><\/lineargradient><\/defs><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 448 512\" aria-hidden=\"true\" width=\"32\" height=\"32\"><path d=\"M272 48a48 48 0 1 0 -96 0 48 48 0 1 0 96 0zm-8 187.3l47.4 57.1c11.3 13.6 31.5 15.5 45.1 4.2s15.5-31.5 4.2-45.1l-73.7-88.9c-18.2-22-45.3-34.7-73.9-34.7H177.1c-33.7 0-64.9 17.7-82.3 46.6l-58.3 97c-9.1 15.1-4.2 34.8 10.9 43.9s34.8 4.2 43.9-10.9L120 256.9V480c0 17.7 14.3 32 32 32s32-14.3 32-32V352h16V480c0 17.7 14.3 32 32 32s32-14.3 32-32V235.3zM352 376c0-4.4 3.6-8 8-8s8 3.6 8 8V488c0 13.3 10.7 24 24 24s24-10.7 24-24V376c0-30.9-25.1-56-56-56s-56 25.1-56 56v8c0 13.3 10.7 24 24 24s24-10.7 24-24v-8z\"\/><\/svg><\/div><div class=\"stk--inner-svg stk--icon-2\" style=\"display:none\"><svg style=\"height:0;width:0\"><defs><lineargradient id=\"linear-gradient-725ba41\" x1=\"0\" x2=\"100%\" y1=\"0\" y2=\"0\"><stop offset=\"0%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-725-ba-41-color-1)\"><\/stop><stop offset=\"100%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-725-ba-41-color-2)\"><\/stop><\/lineargradient><\/defs><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 448 512\" aria-hidden=\"true\" width=\"32\" height=\"32\"><path d=\"M224 256A128 128 0 1 0 224 0a128 128 0 1 0 0 256zm-45.7 48C79.8 304 0 383.8 0 482.3C0 498.7 13.3 512 29.7 512H418.3c16.4 0 29.7-13.3 29.7-29.7C448 383.8 368.2 304 269.7 304H178.3z\"\/><\/svg><\/div><\/span><\/div>\n\n\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-0f5bdae\" id=\"acceso\" data-block-id=\"0f5bdae\"><style>.stk-0f5bdae .stk-block-heading__text{color:#000000 !important;font-weight:500 !important;font-family:\"ArgentumSans\", Sans-serif !important;}<\/style><h4 class=\"stk-block-heading__text has-text-color\"><span style=\"color: #000000;\" class=\"stk-highlight\">Chronic diseases related to aging<\/span><\/h4><\/div>\n<\/div><\/div>\n<\/div><\/div><\/summary>\n\n\n\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-83f0709 stk-block-accordion__content\" data-v=\"4\" data-block-id=\"83f0709\"><style>.stk-83f0709 {margin-top:-30px !important;}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-83f0709-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-83f0709-inner-blocks\">\n<ul class=\"wp-block-list\">\n<li>This program is dedicated to research into the biological basis of major human diseases and the search for new therapies to treat them. Given that the severity of most of these diseases increases dramatically with age and the aging population in the European Union, the economic consequences of these pathologies are enormous. Furthermore, most age-related diseases have a complex course and affect various bodily systems, thus requiring a preventative approach, a comprehensive therapeutic strategy, and strict lifestyle management.<br>List of groups (click to expand information)\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/portalciencia.ull.es\/grupos\/6455\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Chronic kidney disease, diabetes, and kidney transplant complications<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/82291\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Esteban Porrini<\/a>,\u00a0<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/823392\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Domingo J. Hern\u00e1ndez Marrero<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/portalciencia.ull.es\/grupos\/6576\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Inflammatory and neoplastic diseases of the gastrointestinal tract. Prevalent liver diseases<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/82337\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Manuel Hern\u00e1ndez Guerra de Aguilar<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/portalciencia.ull.es\/grupos\/6509\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Pathophysiology of mineralocorticoids<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/81922\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Diego \u00c1lvarez de la Rosa Rodr\u00edguez<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/portalciencia.ull.es\/grupos\/6541\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Drug delivery systems<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/81528\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Araceli Delgado Hern\u00e1ndez<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/investigacion-en-enfermedad-renal-y-cardiovascular\/\" target=\"_blank\" rel=\"noreferrer noopener\">Research in kidney and cardiovascular disease<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/205540\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Juan F. Navarro Gonz\u00e1lez<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/respuesta-inflamatoria-y-dano-tisular-en-la-artritis-reumatoide\/\" target=\"_blank\" rel=\"noreferrer noopener\">Inflammatory response and tissue damage in rheumatoid arthritis<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/81156\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Federico D\u00edaz Gonz\u00e1lez<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/fisiopatologia-del-metabolismo-mineral\/\" target=\"_blank\" rel=\"noreferrer noopener\">Pathophysiology of mineral metabolism<\/a>\u00a0(Dr. Javier Donate Correa)<\/li>\n\n\n\n<li>Telomeric integrity in aging and cancer (<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/1244729\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Jonathan Barroso Gonz\u00e1lez<\/a>)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div><\/div><\/div>\n<\/details>\n\n\n\n<details class=\"wp-block-stackable-accordion stk-block-accordion stk-inner-blocks stk-block-content stk-block stk-1172c07 is-style-default\" id=\"neurobiologia-y-enfermedades-del-sistema-nervioso\" data-block-id=\"1172c07\"><style>.stk-1172c07 {border-style:solid !important;border-top-width:0px !important;border-right-width:0px !important;border-bottom-width:1px !important;border-left-width:0px !important;margin-bottom:11px !important;}<\/style>\n<summary class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-4a03dc7 stk--container-small stk-block-accordion__heading\" data-v=\"4\" data-block-id=\"4a03dc7\"><style>.stk-4a03dc7 {padding-top:2px !important;padding-right:2px !important;padding-bottom:2px !important;padding-left:2px !important;}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-4a03dc7-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-4a03dc7-inner-blocks\">\n<div class=\"wp-block-stackable-icon-label stk-block-icon-label stk-block stk-f9c7ee5\" data-block-id=\"f9c7ee5\"><style>.stk-f9c7ee5 .stk-inner-blocks{gap:39px !important;}@media screen and (max-width: 1023px){.stk-f9c7ee5 .stk-inner-blocks{gap:39px !important;}}@media screen and (max-width: 767px){.stk-f9c7ee5 .stk-inner-blocks{gap:39px !important;}}<\/style><div class=\"stk-row stk-inner-blocks stk-block-content\">\n<div class=\"wp-block-stackable-icon stk-block-icon stk-block stk-c303281\" data-block-id=\"c303281\"><style>.stk-c303281 .stk--svg-wrapper .stk--inner-svg svg:last-child{height:25px !important;width:25px !important;}.stk-c303281 .stk--svg-wrapper .stk--inner-svg svg:last-child, .stk-c303281 .stk--svg-wrapper .stk--inner-svg svg:last-child :is(g, path, rect, polygon, ellipse){fill:#5c068c !important;}<\/style><span class=\"stk--svg-wrapper stk--has-icon2\"><div class=\"stk--inner-svg\"><svg style=\"height:0;width:0\"><defs><lineargradient id=\"linear-gradient-c303281\" x1=\"0\" x2=\"100%\" y1=\"0\" y2=\"0\"><stop offset=\"0%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-c-303281-color-1)\"><\/stop><stop offset=\"100%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-c-303281-color-2)\"><\/stop><\/lineargradient><\/defs><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 512 512\" aria-hidden=\"true\" width=\"32\" height=\"32\"><path d=\"M184 0c30.9 0 56 25.1 56 56V456c0 30.9-25.1 56-56 56c-28.9 0-52.7-21.9-55.7-50.1c-5.2 1.4-10.7 2.1-16.3 2.1c-35.3 0-64-28.7-64-64c0-7.4 1.3-14.6 3.6-21.2C21.4 367.4 0 338.2 0 304c0-31.9 18.7-59.5 45.8-72.3C37.1 220.8 32 207 32 192c0-30.7 21.6-56.3 50.4-62.6C80.8 123.9 80 118 80 112c0-29.9 20.6-55.1 48.3-62.1C131.3 21.9 155.1 0 184 0zM328 0c28.9 0 52.6 21.9 55.7 49.9c27.8 7 48.3 32.1 48.3 62.1c0 6-.8 11.9-2.4 17.4c28.8 6.2 50.4 31.9 50.4 62.6c0 15-5.1 28.8-13.8 39.7C493.3 244.5 512 272.1 512 304c0 34.2-21.4 63.4-51.6 74.8c2.3 6.6 3.6 13.8 3.6 21.2c0 35.3-28.7 64-64 64c-5.6 0-11.1-.7-16.3-2.1c-3 28.2-26.8 50.1-55.7 50.1c-30.9 0-56-25.1-56-56V56c0-30.9 25.1-56 56-56z\"\/><\/svg><\/div><div class=\"stk--inner-svg stk--icon-2\" style=\"display:none\"><svg style=\"height:0;width:0\"><defs><lineargradient id=\"linear-gradient-c303281\" x1=\"0\" x2=\"100%\" y1=\"0\" y2=\"0\"><stop offset=\"0%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-c-303281-color-1)\"><\/stop><stop offset=\"100%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-c-303281-color-2)\"><\/stop><\/lineargradient><\/defs><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 512 512\" aria-hidden=\"true\" width=\"32\" height=\"32\"><path d=\"M228.3 469.1L47.6 300.4c-4.2-3.9-8.2-8.1-11.9-12.4h87c22.6 0 43-13.6 51.7-34.5l10.5-25.2 49.3 109.5c3.8 8.5 12.1 14 21.4 14.1s17.8-5 22-13.3L320 253.7l1.7 3.4c9.5 19 28.9 31 50.1 31H476.3c-3.7 4.3-7.7 8.5-11.9 12.4L283.7 469.1c-7.5 7-17.4 10.9-27.7 10.9s-20.2-3.9-27.7-10.9zM503.7 240h-132c-3 0-5.8-1.7-7.2-4.4l-23.2-46.3c-4.1-8.1-12.4-13.3-21.5-13.3s-17.4 5.1-21.5 13.3l-41.4 82.8L205.9 158.2c-3.9-8.7-12.7-14.3-22.2-14.1s-18.1 5.9-21.8 14.8l-31.8 76.3c-1.2 3-4.2 4.9-7.4 4.9H16c-2.6 0-5 .4-7.3 1.1C3 225.2 0 208.2 0 190.9v-5.8c0-69.9 50.5-129.5 119.4-141C165 36.5 211.4 51.4 244 84l12 12 12-12c32.6-32.6 79-47.5 124.6-39.9C461.5 55.6 512 115.2 512 185.1v5.8c0 16.9-2.8 33.5-8.3 49.1z\"\/><\/svg><\/div><\/span><\/div>\n\n\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-4eea02f\" id=\"acceso\" data-block-id=\"4eea02f\"><style>.stk-4eea02f .stk-block-heading__text{color:#000000 !important;font-weight:500 !important;font-family:\"ArgentumSans\", Sans-serif !important;}<\/style><h4 class=\"stk-block-heading__text has-text-color\"><span style=\"color: #000000;\" class=\"stk-highlight\">Neurobiology and diseases of the nervous system<\/span><\/h4><\/div>\n<\/div><\/div>\n<\/div><\/div><\/summary>\n\n\n\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-e4a585c stk-block-accordion__content\" data-v=\"4\" data-block-id=\"e4a585c\"><style>.stk-e4a585c {margin-top:-30px !important;}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-e4a585c-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-e4a585c-inner-blocks\">\n<ul class=\"wp-block-list\">\n<li>This program integrates research groups studying the biology and pathology of the nervous system, with a particular emphasis on neurodegenerative diseases, the molecular and cellular bases of neuronal vulnerability, the development of animal models for studying the genetic basis of neurodegeneration, and the analysis of global brain function and the biological basis of cognition. At the cellular and molecular level, the role of specific membrane proteins (ion channels and transporters) and signaling molecules in different types of excitable cells is studied using electrophysiological, molecular, and morphological approaches. An emerging platform within this program is dedicated to the development of novel animal models of neurodegenerative diseases. Several lines of research focus on analyzing the human brain as a whole using electrophysiological and neuroimaging techniques. Together, this approach ensures a holistic view of the human nervous system that, once scaled up, will be useful in the search for new therapies for neurodegenerative diseases.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">List of groups (click to expand information)<\/h4>\n\n\n\n<h4 class=\"wp-block-heading\">A. Cellular and molecular neurobiology<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/portalciencia.ull.es\/grupos\/6376\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Molecular basis of human channelopathies (MOLCAN)<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/82446\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Teresa Gir\u00e1ldez Fern\u00e1ndez<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/portalciencia.ull.es\/grupos\/6418\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Molecular mechanisms in neurodegeneration<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/81920\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. \u00c1ngel Acebes Vindel<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/modelos-animales-en-neurodegeneracion\/\" target=\"_blank\" rel=\"noreferrer noopener\">Animal models of neurodegeneration<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/205538\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Abraham Acevedo Arozena<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/portalciencia.ull.es\/grupos\/6353\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Neuronal vulnerability and plasticity<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/82447\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Tom\u00e1s Gonz\u00e1lez Hern\u00e1ndez<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/neurologia-y-neurobiologia-experimental-nne\/\" target=\"_blank\" rel=\"noreferrer noopener\">Neurology and Experimental Neurobiology (NE)<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/81932\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Manuel Rodr\u00edguez D\u00edaz<\/a>)<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">B. Clinical and Cognitive Neuroscience<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/laboratorio-de-imagen-cerebral\/\" target=\"_blank\" rel=\"noreferrer noopener\">Brain Imaging Laboratory<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/81758\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Niels Janssen<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/portalciencia.ull.es\/grupos\/6317\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Electrical engineering and bioengineering<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/80814\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Ernesto Pereda de Pablo<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/neurociencia-cognitiva-y-psicolinguistica\/\" target=\"_blank\" rel=\"noreferrer noopener\">Cognitive neuroscience and psycholinguistics<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/81614\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Horacio A. Barber Friend<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/portalciencia.ull.es\/grupos\/6274\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Neurochemistry and Neuroimaging<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/81174\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Jos\u00e9 Luis Gonz\u00e1lez Mora<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/neurociencia-clinica\/\" target=\"_blank\" rel=\"noreferrer noopener\">Clinical neuroscience<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/82290\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Julio Plata Bello<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/portalciencia.ull.es\/grupos\/6933\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">AFM-NANO \u2013 Advanced Functional Materials and Nanoscience<\/a>\u00a0(<a href=\"https:\/\/portalciencia.ull.es\/investigadores\/82481\/detalle\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. David D\u00edaz D\u00edaz<\/a>)<\/li>\n<\/ul>\n<\/div><\/div><\/div>\n<\/details>\n<\/div><\/div><\/div>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Programas, grupos y l\u00edneas de investigaci\u00f3n El Instituto Universitario de Desarrollo Regional (IUDR) de La Universidad de La Laguna es un centro de investigaci\u00f3n y formaci\u00f3n especializada. El objetivo prioritario del Instituto es el de promover una plataforma de investigaci\u00f3n, de car\u00e1cter abierto y del m\u00e1s alto nivel acad\u00e9mico, en el marco amplio de las&#8230;<\/p>","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"templates\/template-100-width.php","meta":{"footnotes":""},"class_list":["post-116","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/wp-json\/wp\/v2\/pages\/116","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/wp-json\/wp\/v2\/comments?post=116"}],"version-history":[{"count":42,"href":"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/wp-json\/wp\/v2\/pages\/116\/revisions"}],"predecessor-version":[{"id":875,"href":"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/wp-json\/wp\/v2\/pages\/116\/revisions\/875"}],"wp:attachment":[{"href":"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/en\/wp-json\/wp\/v2\/media?parent=116"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}