{"id":278,"date":"2021-03-11T11:52:24","date_gmt":"2021-03-11T11:52:24","guid":{"rendered":"http:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/?page_id=278"},"modified":"2024-09-11T09:26:22","modified_gmt":"2024-09-11T09:26:22","slug":"respuesta-inflamatoria-y-dano-tisular-en-la-artritis-reumatoide","status":"publish","type":"page","link":"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/respuesta-inflamatoria-y-dano-tisular-en-la-artritis-reumatoide\/","title":{"rendered":"Respuesta inflamatoria y da\u00f1o tisular en la artritis reumatoide"},"content":{"rendered":"<p>[vc_row][vc_column][vc_column_text]<\/p>\n<div class=\"page-header\">\n<h1>Respuesta inflamatoria y da\u00f1o tisular en la artritis reumatoide<\/h1>\n<\/div>\n<div class=\"content\">\n<h4><b>Investigador responsable<\/b><\/h4>\n<table class=\"jefe\">\n<tbody>\n<tr>\n<td class=\"provisional\"><\/td>\n<td><strong><a href=\"https:\/\/portalciencia.ull.es\/investigadores\/81156\/detalle\" target=\"_blank\" rel=\"noopener\" target=\"_blank\" rel=\"noopener\">Jos\u00e9 Federico D\u00edaz Gonz\u00e1lez<\/a>, MD, PhD<\/strong><\/p>\n<p>Catedr\u00e1tico de Medicina; Departamento de Medicina Interna, Dermatolog\u00eda y Psiquiatr\u00eda, ULL \u2013 Jefe del Servicio de Reumatolog\u00eda, HUC<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><b>Colaboradores doctores<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Javier Rafael Castro Hern\u00e1ndez, PhD (Profesor Ayudante Doctor; Departamento de Medicina F\u00edsica y Farmacolog\u00eda, ULL \u2013 hasta 05\/2023)<\/span><\/li>\n<\/ul>\n<p><b>Colaboradores doctores asistenciales<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Judith M\u00aa L\u00f3pez Fern\u00e1ndez, MD, PhD (M\u00e9dico Adjunto; Servicio de Endocrinolog\u00eda, HUC)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Iv\u00e1n Ferraz Amaro, MD, PhD (M\u00e9dico Adjunto; Servicio de Reumatolog\u00eda, HUC)<\/span><\/li>\n<\/ul>\n<p><b>Estudiantes de doctorado e investigadores en formaci\u00f3n<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sergio Iv\u00e1n Santos Concepci\u00f3n (Programa de Doctorado Ciencias de la Salud ULL, FIISC, Sociedad Espa\u00f1ola de Reumatolog\u00eda)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">No\u00e9 Adal Brito Garc\u00eda (Programa de Doctorado Ciencias M\u00e9dicas y Farmac\u00e9uticas, Desarrollo y Calidad de Vida, ULL)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Virginia Dom\u00ednguez Pimentel (Programa de Doctorado Ciencias de la Salud, ULL)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ana Bel\u00e9n Llanos Mart\u00edn (Programa de Doctorado Ciencias de la Salud ULL, tesis defendida 19\/05\/2023)<\/span><\/li>\n<\/ul>\n<p><b>L\u00edneas de investigaci\u00f3n<\/b><\/p>\n<ul>\n<li aria-level=\"1\"><span style=\"font-weight: 400;\">Determinaci\u00f3n del papel de los radicales libres de oxigeno en la regulaci\u00f3n de las primeras etapas de la respuesta inflamatoria<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><span style=\"font-weight: 400;\">Estudio del efecto in vivo de sustancias con actividad anti-L-selectina en la migraci\u00f3n de neutr\u00f3filos<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><span style=\"font-weight: 400;\">Estudio del papel modulador de los receptores adren\u00e9rgico alfa 2 en la respuesta inflamatoria aguda<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><span style=\"font-weight: 400;\">La implicaci\u00f3n de citocinas y quimiocinas en la patogenia de la artritis reumatoide, la artropat\u00eda psori\u00e1sica y el s\u00edndrome de Sj\u00f6gren<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><span style=\"font-weight: 400;\">Estudio de la capacidad del tejido pancre\u00e1tico en la diferenciaci\u00f3n de las c\u00e9lulas madre adultas en c\u00e9lulas endocrinas pancre\u00e1ticas<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><span style=\"font-weight: 400;\">Modulaci\u00f3n de la respuesta inflamatoria aguda y cr\u00f3nica de los receptores LXR<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><span style=\"font-weight: 400;\">Actividad f\u00edsica en pacientes con enfermedades articulares cr\u00f3nicas. Relaci\u00f3n entre actividad cl\u00ednica y capacidad de movimiento. An\u00e1lisis de la actividad f\u00edsica en pacientes con artritis psori\u00e1sica<\/span><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Efecto de las citocinas y la respuesta inflamatoria sobre la resistencia a la insulina, el flujo de colesterol y PCSK9<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Adiposidad abdominal y composici\u00f3n corporal en pacientes con artritis reumatoide<\/span><\/li>\n<\/ul>\n<p><b>Proyectos financiados<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Regulation of fat inflammation in human obesity. Role of chemokine system and alpha2-adrenergic receptors in macrophage accumulation in adipose tissue (PI21\/00406). IP: Federico D\u00edaz. Instituto de Salud Carlos III (01\/2022 &#8211; 12\/2024, 120.000 \u20ac)<\/span><\/li>\n<\/ul>\n<p><b>Publicaciones 2023<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Montero-Pastor N, S\u00e1nchez-Costa JT, Guerra-Rodr\u00edguez M, S\u00e1nchez-Alonso F, Moriano C, Loricera J, <\/span><b>D\u00edaz-Gonz\u00e1lez F<\/b><span style=\"font-weight: 400;\">. Development of a web tool to calculate the cumulative dose of glucocorticoids. <\/span><i><span style=\"font-weight: 400;\">Reumatologia Clinica<\/span><\/i><span style=\"font-weight: 400;\">. 2023;19(1):1-5. DOI: 10.1016\/J.REUMA.2022.04.004<\/span><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Michelsen B, \u00d8stergaard M, Nissen MJ, Ciurea A, M\u00f6ller B, \u00d8rnbjerg LM, et al. (<\/span><b>D\u00edaz-Gonz\u00e1lez F)<\/b><span style=\"font-weight: 400;\">, Bustabad-Reyes S. Differences and similarities between the EULAR\/ASAS-EULAR and national recommendations for treatment of patients with psoriatic arthritis and axial spondyloarthritis across Europe. <\/span><i><span style=\"font-weight: 400;\">The Lancet Regional Health &#8211; Europe<\/span><\/i><span style=\"font-weight: 400;\">. 2023 Oct;33:100706. DOI: 10.1016\/j.lanepe.2023.100706<\/span><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u00c1lvaro-Gracia JM, Sanchez-Piedra C, Culqui D, Rosello R, Garcia-Dorta A, Campos C, Manrique-Arija S, Ruiz-Montesinos D, Ros-Vilamajo I, Rodr\u00edguez-Lozano C, Freire-Gonz\u00e1lez M, Caliz R, Bohorquez C, Mateo Soria L, Busquets N, Castrejon I, S\u00e1nchez-Alonso F, Gonz\u00e1lez-D\u00e1vila E, <\/span><b>Diaz-Gonzalez F<\/b><span style=\"font-weight: 400;\">. Effects of COVID-19 vaccination on disease activity in patients with rheumatoid arthritis and psoriatic arthritis on targeted therapy in the COVIDSER study. <\/span><i><span style=\"font-weight: 400;\">RMD open<\/span><\/i><span style=\"font-weight: 400;\">. 2023 Mar;9(1):e002936. DOI: 10.1136\/rmdopen-2022-002936<\/span><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Torre Alonso JC, Almod\u00f3var Gonz\u00e1lez R, Montilla Morales C, Sanz Sanz J, <\/span><b>D\u00edaz Gonz\u00e1lez F<\/b><span style=\"font-weight: 400;\">, Pascual Alfonso E, Gratac\u00f3s J. Expert recommendations for the use of apremilast in psoriatic arthritis. <\/span><i><span style=\"font-weight: 400;\">Reumatologia Clinica<\/span><\/i><span style=\"font-weight: 400;\">. 2023;19(1):34-44. DOI: 10.1016\/J.REUMA.2022.01.002<\/span><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pombo-Su\u00e1rez M, Seoane-Mato D, <\/span><b>D\u00edaz-Gonz\u00e1lez F<\/b><span style=\"font-weight: 400;\">, S\u00e1nchez-Alonso F, S\u00e1nchez-Jare\u00f1o M, Cea-Calvo L, Castrej\u00f3n I. Four-years retention rate of golimumab administered after discontinuation of non-TNF inhibitors in patients with inflammatory rheumatic diseases. <\/span><i><span style=\"font-weight: 400;\">Advances in Rheumatology<\/span><\/i><span style=\"font-weight: 400;\">. 2023 Jun 7;63(1):25. DOI: 10.1186\/s42358-023-00296-1<\/span><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Garc\u00eda-Gonz\u00e1lez M, G\u00f3mez-Bernal F, Quevedo-Abeledo JC, Fern\u00e1ndez-Cladera Y, Gonz\u00e1lez-Rivero AF, de Vera-Gonz\u00e1lez A, de la Rua-Figueroa I, L\u00f3pez-Mejias R, <\/span><b>D\u00edaz-Gonz\u00e1lez F<\/b><span style=\"font-weight: 400;\">, Gonz\u00e1lez-Gay M\u00c1, Ferraz-Amaro I. Full characterization of the three pathways of the complement system in patients with systemic lupus erythematosus. <\/span><i><span style=\"font-weight: 400;\">Frontiers in Immunology<\/span><\/i><span style=\"font-weight: 400;\">. 2023 Apr 21:14:1167055. DOI: 10.3389\/fimmu.2023.1167055<\/span><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Garc\u00eda-Gonz\u00e1lez M, G\u00f3mez-Bernal F, Quevedo-Abeledo JC, Fern\u00e1ndez-Cladera Y, Gonz\u00e1lez-Rivero AF, L\u00f3pez-Mej\u00edas R, <\/span><b>D\u00edaz-Gonz\u00e1lez F<\/b><span style=\"font-weight: 400;\">, Gonz\u00e1lez-Gay M\u00c1, Ferraz-Amaro I. HDL Cholesterol Efflux and the Complement System Are Linked in Systemic Lupus Erythematosus. <\/span><i><span style=\"font-weight: 400;\">Journal of Clinical Medicine<\/span><\/i><span style=\"font-weight: 400;\">. 2023;12(16). DOI: 10.3390\/jcm12165405<\/span><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pombo-Su\u00e1rez M, Seoane-Mato D, <\/span><b>D\u00edaz-Gonz\u00e1lez F<\/b><span style=\"font-weight: 400;\">, Cea-Calvo L, S\u00e1nchez-Alonso F, S\u00e1nchez-Jare\u00f1o M, Jovani V, Garc\u00eda-Magall\u00f3n B, Mart\u00ednez-Gonz\u00e1lez O, Campos-Fern\u00e1ndez C, Manero J, D\u00edaz-Torne C, Boh\u00f3rquez C, Ros-Vilamaj\u00f3 I, P\u00e9rez-Vera Y, Castrej\u00f3n I. Long-term retention of golimumab treatment in clinical practice in a large cohort of patients with rheumatoid arthritis, axial spondyloarthritis and psoriatic arthritis. <\/span><i><span style=\"font-weight: 400;\">Musculoskeletal Care<\/span><\/i><span style=\"font-weight: 400;\">. 2023 Mar;21(1):189-197. DOI: 10.1002\/msc.1684<\/span><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>D\u00edaz-Gonz\u00e1lez F<\/b><span style=\"font-weight: 400;\">, Hern\u00e1ndez-Hern\u00e1ndez MV. Rheumatoid arthritis. <\/span><i><span style=\"font-weight: 400;\">Medicina Clinica<\/span><\/i><span style=\"font-weight: 400;\">. 2023 Dec 22;161(12):533-542. DOI: 10.1016\/j.medcli.2023.07.014<\/span><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ferraz-Amaro I, Santos-Concepci\u00f3n S, Castro J, Hern\u00e1ndez-Hern\u00e1ndez MV, Tejera-Segura B, Luna C, Delgado-Fr\u00edas E, <\/span><b>D\u00edaz-Gonz\u00e1lez F<\/b><span style=\"font-weight: 400;\">. Tocilizumab-related hypertriglyceridemia is independent of key molecules regulating lipid metabolism. <\/span><i><span style=\"font-weight: 400;\">European Journal of Clinical Investigation<\/span><\/i><span style=\"font-weight: 400;\">. 2023 Sep;53(9):e14006. DOI: 10.1111\/eci.14006<\/span><\/li>\n<\/ul>\n<p><b>Otras publicaciones representativas de los \u00faltimos a\u00f1os<\/b><\/p>\n<ul>\n<li aria-level=\"1\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Dom%C3%ADnguez-Luis%20MJ%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=30443903\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Dom\u00ednguez-Luis MJ<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Armas-Gonz%C3%A1lez%20E%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=30443903\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Armas-Gonz\u00e1lez E<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Herrera-Garc%C3%ADa%20A%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=30443903\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Herrera-Garc\u00eda A<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Arce-Franco%20M%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=30443903\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Arce-Franco M<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Feria%20M%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=30443903\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Feria M<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Vicente-Manzanares%20M%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=30443903\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Vicente-Manzanares M<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Mart%C3%ADnez-Ruiz%20A%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=30443903\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Mart\u00ednez-Ruiz A<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=S%C3%A1nchez-Madrid%20F%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=30443903\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">S\u00e1nchez-Madrid F<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=D%C3%ADaz-Gonz%C3%A1lez%20F%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=30443903\" target=\"_blank\" rel=\"noopener\"><b>D\u00edaz-Gonz\u00e1lez F<\/b><\/a><span style=\"font-weight: 400;\">. L-selectin expression is regulated by CXCL8-induced reactive oxygen species produced during human neutrophil rolling. <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=L-selectin+expression+is+regulated+by+CXCL8-induced+reactive+oxygen+species+produced+during+human+neutrophil+rolling\" target=\"_blank\" rel=\"noopener\"><i><span style=\"font-weight: 400;\">Eur J Immunol<\/span><\/i><span style=\"font-weight: 400;\">.<\/span><\/a><span style=\"font-weight: 400;\"> 2019 Mar;49(3):386-397. DOI: 10.1002\/eji.201847710<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><span style=\"font-weight: 400;\">\u00c1lvaro-Gracia JM, Jover JA, Garc\u00eda-Vicu\u00f1a R, Carre\u00f1o L, Alonso A, Marsal S, Blanco F, Mart\u00ednez-Taboada VM, Taylor P, Mart\u00edn-Mart\u00edn C, DelaRosa O, Tagarro I, <\/span><b>D\u00edaz-Gonz\u00e1lez F.<\/b><span style=\"font-weight: 400;\"> Intravenous administration of expanded allogeneic adipose-derived mesenchymal stem cells in refractory rheumatoid arthritis (Cx611): results of a multicentre, dose escalation, randomised, single-blind, placebo-controlled phase Ib\/IIa clinical trial. <\/span><i><span style=\"font-weight: 400;\">Ann Rheum Dis<\/span><\/i><span style=\"font-weight: 400;\">. 2017 Jan;76(1):196-202. DOI: 10.1136\/annrheumdis-2015-208918<\/span><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cutolo M, Myerson GE, Fleischmann RM, Liote F, <\/span><b>D\u00edaz-Gonz\u00e1lez F<\/b><span style=\"font-weight: 400;\">, Van den Bosch F, Mazo-Ortega H, Feist E, Shan K, Hu C, Stevens RM, Poder A. A phase III, randomized, controlled trial of Apremilast in patients with psoriatic arthritis: resilys of the PALACE 2 trial. <\/span><i><span style=\"font-weight: 400;\">J Rheumatol<\/span><\/i><span style=\"font-weight: 400;\">. 2016 Sep;43(9):1724-34. DOI: 10.3899\/jrheum.151376<\/span><\/li>\n<\/ul>\n<\/div>\n<p>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text] Respuesta inflamatoria y da\u00f1o tisular en la artritis reumatoide Investigador responsable Jos\u00e9 Federico D\u00edaz Gonz\u00e1lez, MD, PhD Catedr\u00e1tico de Medicina; Departamento de Medicina Interna, Dermatolog\u00eda y Psiquiatr\u00eda, ULL \u2013 Jefe del Servicio de Reumatolog\u00eda, HUC Colaboradores doctores Javier Rafael Castro Hern\u00e1ndez, PhD (Profesor Ayudante Doctor; Departamento de Medicina F\u00edsica y Farmacolog\u00eda, ULL \u2013 hasta&#8230;<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"templates\/template-no-title.php","meta":[],"_links":{"self":[{"href":"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/wp-json\/wp\/v2\/pages\/278"}],"collection":[{"href":"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/wp-json\/wp\/v2\/comments?post=278"}],"version-history":[{"count":5,"href":"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/wp-json\/wp\/v2\/pages\/278\/revisions"}],"predecessor-version":[{"id":604,"href":"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/wp-json\/wp\/v2\/pages\/278\/revisions\/604"}],"wp:attachment":[{"href":"https:\/\/www.ull.es\/institutos\/instituto-tecnologias-biomedicas\/wp-json\/wp\/v2\/media?parent=278"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}