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Aura Carreira, que impartir\u00e1 la charla \u00abBRCA2 variant functional analysis illuminates genome\u2011maintenance defects driving tumorigenesis\u00bb.<\/div>\n<div><\/div>\n<div>St\u00e9phane Koundrioukoff es investigador en el Centre National de la Recherche Scientifique (CNRS) y responsable de la plataforma de peinado molecular de ADN (DNA combing). Desarrolla su labor en el estudio de la din\u00e1mica cromos\u00f3mica y su trabajo se centra en el an\u00e1lisis del estr\u00e9s de replicaci\u00f3n del ADN, la caracterizaci\u00f3n de los sitios fr\u00e1giles cromos\u00f3micos y los mecanismos moleculares que originan la inestabilidad gen\u00f3mica en el c\u00e1ncer.<\/div>\n<div><\/div>\n<div>Aura Carreira es investigadora principal en el Centro de Biolog\u00eda Molecular Severo Ochoa (CBMSO, CSIC-UAM). Dirige el grupo de investigaci\u00f3n centrado en la recombinaci\u00f3n hom\u00f3loga y la estabilidad del genoma, y su trabajo se centra en los mecanismos moleculares de reparaci\u00f3n del ADN, las funciones biol\u00f3gicas del supresor tumoral BRCA2 y las v\u00edas patol\u00f3gicas vinculadas a la susceptibilidad y desarrollo del c\u00e1ncer de mama y ovario hereditario.<\/div>\n<div><\/div>\n<div>Como todos los seminarios que se celebrar\u00e1n a lo largo de este a\u00f1o, adem\u00e1s de presencialmente en la Sala de Seminarios del ITB, podr\u00e1n seguirse a trav\u00e9s del siguiente <a href=\"http:\/\/meet.google.com\/nzo-cqni-jdp\" target=\"_blank\" rel=\"noopener\">enlace de Google 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