The Instituto Universitario de Bio-Orgánica “Antonio González” (IUBO-AG) is a multidisciplinary research center oriented to the investigation of Bioactive Natural Products. The Institute was started up in the 1960’s with the need to study the secondary metabolites produced by marine and terrestrial organisms, thus providing a new source of unique compounds. Today aims of the Institute are the isolation of pharmacologically active substances from natural sources, biosynthesis, microorganism cultures, biotechnology and total synthesis. In addition biological evaluation, toxin isolation and production, NMR studies of biological process, natural insecticide and repellents, etc. are research areas of current interest.