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Fluorescent beta-blocker (+/-)-RCTM-3 of the β-adrenergic receptors.

Sciences

Fluorescent beta-blocker (+/-)-RCTM-3 of type β adrenergic receptors corresponding to the chemical structure of propranolol, with the 1-naphthol ring replaced by 9-hydroxy-4-methoxyacridine. The resulting compound is a weak base with high lipophilicity and a structure that makes it strongly fluorescent and chemically stable.

Competitive advantage

The compound exhibits a very high quantum light efficiency.

It is a highly efficient secretory organelle marker for use in standard epifluorescence microscopy.

Its enormous quantum efficiency makes it possible to obtain high-quality images with the lasers commonly used in confocal or vanishing-wave microscopy.

Inventors from the University of La Laguna

Joint owner entity

  • Spanish National Research Council (CSIC)
  • Patent Information
  • Patent number: P200801297
  • Priority date: 22/04/2008
  • State: Unlicensed
  • Original document