Compounds for the treatment of diseases caused by oxalate accumulation. The present invention relates to the use of salicylic acid derivatives for the treatment of diseases or pathologies related to the activity of the GO and/or PRODH2 enzymes. In particular, for diseases related to an excess of oxalate and for the treatment of patients with renal insufficiency (uremia or hyperazotemia) undergoing hemodialysis or peritoneal dialysis; especially for patients treated with ascorbic acid (vitamin C), which is metabolized to oxalate, or for patients with fibromyalgia and vulvar pain.