Hybrid nanoparticles composed of lipids and polymers that can be used as carrier particles or “carriers” of a therapeutically effective agent, where the therapeutically effective agent is a gapmer oligonucleotide, methods for their preparation and their uses in medicine.
Treatment of bone loss in osteoporosis and type II diabetes.
– Reduced side effects compared to current therapies.
– Increased bone formation.
– Decreased bone resorption.