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AGL2017-89257-P. Analysis of plastic migrants using advanced analytical techniques combined with alternative extraction techniques in agri-food samples (PLASTEX)

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Several international agencies have recently requested more information on plastic migrants in order to implement stricter regulations, as plastics, along with other endocrine disruptors, have become cocktails of toxic substances with multiple adverse health effects to which the global population is exposed daily. Any high-quality data generated across the various strategic sectors where plastic is used, whether occasionally or regularly, will allow for further regulation of its use and the establishment of corrective measures to minimize the harm to consumers.
It is clear that the food sector is one of the areas where some information exists, but this needs to be expanded and updated with data on the intake of food products in contact with plastic materials (recycled or not) during processing or distribution. To this end, it is necessary to establish highly selective and sensitive analytical protocols that allow for the reliable determination of migration levels of these substances into food products in contact with them. Miniaturized extraction techniques combined with the use of novel extraction materials offer a very useful alternative for this determination. For this purpose, it is essential to combine them with separation techniques using highly selective detectors, such as mass spectrometry, in order to achieve reliable identification and quantification. In this regard, the use of magnetized extraction materials, such as graphene oxide or ionic liquids, among others, would allow for selective extraction, thus ensuring greater reliability in the determination of these substances in food matrices. Likewise, the development of sensors that allow for the rapid determination of these substances in such complex matrices is also of great interest.

This proposal aims to conduct a comprehensive study, using state-of-the-art analytical tools, of the largest possible number of migrating substances from plastics—some known and others unknown—into commonly consumed foods such as milk, dairy products, and soy beverages, as well as other products in our environment and with high consumption both in Spain and worldwide, such as wines. These new studies, which fall within the field of food safety, will allow for continuous assessments of migrant content in widely consumed food products within complex matrices. This will enable reliable risk assessments for consumers and the establishment of preventative measures to safeguard and mitigate health risks.

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Various international agencies have recently requested more information regarding plastic migrants in order to take more stringent regulatory measures, as they have become, along with other endocrine disrupters to which the population is daily exposed, intoxicating cocktails with multiple adverse effects on health. All reliable information generated in the different strategic sectors where plastic is used, as a material of occasional use or not, will allow to regulate its use (recycled or not) even more as well as to establish corrective measurements in order to minimize the damages to which the consumer is exposed to. It is evident that food analysis is one of the fields in which part of such information is known, but it needs to be increased and updated with data concerning the intake of food products in contact with plastic materials during their processing or during their commercialization. In order to do this, it is necessary to establish highly selective and sensitive analytical protocols that allow the feasible determination of the migration levels of these substances to the food in contact with them. Miniaturized extraction techniques combined with the use of new extraction materials are very useful alternatives for their determination. For this purpose, it is essential to combine them with separation techniques coupled to highly selective detectors such as mass spectrometry, in order to carry out a reliable identification and quantification. In this sense, the use of magnetized extraction materials, either graphene oxide or ionic liquids, among others, would allow a selective extraction of them and a greater security in their determination in food matrices. Likewise, the development of sensors that allow a rapid determination of them in such complex matrices is also of great interest.

This proposal intends to make an exhaustive study using the latest analytical tools of the largest number of plastic migrants possible, some known and others unknown, in foods of daily consumption such as milk, dairy products and soy drinks as well as wine, with is a product with a high consumption in Spain and also in the rest of the world. These new studies within the field of food safety will allow continuous assessments of the content of migrants in high consumption food products with a high complexity to estimate the risks of the consumer
and to establish preventive measurements to safeguard and ensure health risks.

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Researcher at the University of La Laguna