Institute of Biomedical Technologies

PRINCIPAL INVESTIGATOR

Julio T. Ávila Marrero

Professor of Biochemistry and Molecular Biology, Department of Biochemistry, Microbiology, Cellular Biology and Genetics, ULL

Pablo Martín Vasallo

Professor of Biochemistry and Molecular Biology, Department of Biochemistry, Microbiology, Cellular Biology and Genetics, ULL

EXTERNAL COLLABORATORS:

  • Manuel José Morales González (Associate Lecturer in Internal Medicine, Head of the Medical Oncology Service, HUNSC)
  • Ángela Palumbo (Medical Director, In vitro Fertilization Centre)
  • Jairo Hernández Hernández (Laboratory Director, In vitro Fertilization Centre)
  • Deborah Rotoli (Visiting Investigator)
  • Rebeca González Fernández (SEGAI technician, ULL)

PHD STUDENTS AND TRAINEES:

  • Rita Marleny Martín Ramírez (PhD student, The Canary Islands Agency of Research, Innovation and Information Sciences, ACIISI)
  • Fabián Leopoldo Poletti Serafini (Traumatology service H. San Juan de Dios, Doctorate Program in Health Sciences)
  • María Adela Rodríguez Fuentes (Radiology Service HUC, Doctorate Program in Health Sciences)
  • Miriam Dorta Suárez (Medical Oncology-HUNSC)

RESEARCH LINES:

  • Gene expression in granulose and cumulus cells during follicular ovarian cancer development in humans.
  • Study of the changes in gene expression associated with the administration of chemotherapy to cancer patients.
  • Molecular Biology and the cellular Na+/K+-ATPase

PUBLICATIONS 2019:

  • Rotoli D,Morales M,Maeso MD,Ávila J,Pérez-Rodríguez ND,Mobasheri A,vanNoorden CJF,Martín-Vasallo P. IQGAP1, AmotL2, and FKBP51 Scaffoldins in the Glioblastoma Microenvironment. J Histochem Cytochem. 2019 Jul;67(7):481-494. doi: 10.1369/0022155419833334
  • Mobasheri A, Matta C, Uzielienè I, Budd E, Martín-Vasallo P, Bernotiene E. The chondrocyte “channelome”: A narrative review. [Le «channelome» du chondrocyte. Revue narrative]. Revue du Rhumatisme (Edition Francaise). 2019 Mar;86(2):147-154. doi: 10.1016/j.rhum.2018.08.001
  • Mobasheri A,Matta C,Uzielienè I,Budd E, Martín-Vasallo P,Bernotiene E. The chondrocyte channelome: A narrative review. Joint Bone Spine. 2019 Jan;86(1):29-35. doi: 10.1016/j.jbspin.2018.01.012

OTHER SELECTED PUBLICATIONS FROM THE LAST 10 YEARS:

  • Rotoli D, Morales M, Del Carmen Maeso M, Del Pino Garcia M, Morales A, Avila J, Martin-Vasallo P. Expression and localization of the immunophilin FKBP51 in colorectal carcinomas and primary metastases, and alterations following oxaliplatin chemotherapy. Oncol Lett. 2016 Aug;12(2):1351-1322. doi: 3892/ol.2016.4772
  • Baker Bechmann M, Rotoli D, Morales M, Maeso M del C, Garcia M, Ávila J, Mobasheri A, Martín-Vasallo P. Na,K-ATPase Isozymes in Colorectal Cancer and Liver Metastases. Front Physiol. 2016 Jan 29;7:9. doi: 10.3389/fphys.2016.00009
  • González-Fernández R, Ávila J, Arteaga MF, Canessa CM, Martín-Vasallo P. The neuronal-specific SGK1.1 (SGK1_v2) kinase as a transcriptional modulator of BAG4, Brox, and PPP1CB genes expression. Int J Mol. Sci. 2015 Apr 2;16(4):7462-77. doi:10.3390/ijms16047462
  • González-Fernández R, Morales M, Avila J, Martín-Vasallo P. Changes in leukocyte gene expression profiles induced by antineoplastic chemotherapy. Oncol Lett. 2012Jun; 3(6):1341-1349. doi: 3892/ol.2012.669
  • Mobasheri A, Trujillo E, Arteaga MF, Martín-Vasallo P. Na(+), K(+)-ATPase Subunit Composition in a Human Chondrocyte Cell Line; evidence for the Presence of A1, A3, B1, B2 and B3 Isoforms. Int J Mol Sci. 2012;13(4):5019-34. doi: 10.3390/ijms13045019