Institute of Biomedical Technologies


Pedro Serrano Aguilar, MD, PhD

Head of SCS Assessment and Planning Service, and Head of the Health Technologies Assessment Unit

Lilisbeth Perestelo Pérez, PhD

Assessment and Planning Service, SCS


  • Iván Castilla Rodríguez, PhD (RedETS contract)
  • María del Mar Trujillo Martín, PhD (RedETS contract)
  • Amado Rivero Santana, PhD (RedETS contract)
  • Ana Toledo Chávarri, PhD (RedETS contract)
  • Tasmania del Pino Sedeño, PhD (RedETS contract)
  • Néstor Benítez, PhD (RedETS contract)
  • Beatriz León Salas, PhD (RedETS contract)
  • Lidia García Pérez (RedETS contract)
  • Yolanda Ramallo Fariña (RedETS contract)
  • Renata Linertova (RedETS contract)
  • Cristina Valcárcel Nazco (RedETS contract)
  • Yolanda Álvarez (RedETS contract)
  • Vanesa Ramos (RedETS contract)
  • Leticia Rodríguez (RedETS contract)


  • Health Assessment Services focusing on telemedicine, health technologies viability assessments and the economic impact of diseases.
  • Health Technologies Assessment, and studies of the effectiveness and efficacy of health technologies through systematic review and cost-effectiveness analysis.
  • Shared decision making through the development, assessment and implementation of techniques and tools that aid shared decision-making.


  • Effectiveness and cost-effectiveness over 5 years for complex ITC knowledge transfer interventions designed for health improvement in DM2 (INDICA-DOS, PI16/00769 – “Efectividad y coste-efectividad de intervenciones complejas de transferencia de conocimiento basadas en TICs a 5 años, para mejorar la salud en pacientes con DM2”). PI: Pedro Serrano. Institute of Health Carlos III (2017-2019, 50,215 €).
  • EUnetHTA Joint Action 3. PI: Pedro Serrano. EU Executive Agency for Health and Consumers (2016-2020, 88,000 €).
  • Health Service Research Network on Chronic Diseases (REDISSEC – «Red de Investigación en Servicios de Salud en Enfermedades Crónicas»). PI: Pedro Serrano. Institute of Health Carlos III 2017-2020, 240,000 €).
  • Improving digital health literacy in Europe. European Commission. PI: Lilisbeth Perestelo. FUNCANIS (2016-2018, 149,875 €).
  • Clinical and economic impact of ozone-therapy on patients waiting for herniated disc surgery (PI17/00120 – “Impacto clínico y económico de la ozonoterapia intradiscal en pacientes en lista de espera para cirugía por hernia de disco”). PI: Renata Linertova. Institute of Health Carlos III (2018-2020, 32,065 €).


  • Vallejo-Torres L, Garcia-Lorenzo B, Castilla I, Valcárcel-Nazco C, Garcia-Perez L, Linertova R, Polentinos-Castro E, Serrano-Aguilar P. On the estimation of the cost- effectiveness threshold: why, what, how? Value in Health. 2016 Jul-Aug;19(5):558-66. doi: 10.1016/j.jval.2016.02.020
  • Lopez-Bastida J, Oliva-Moreno J, Linertová R, Serrano-Aguilar P. Social/economic costs and health-related quality of life in patients with rare diseases in Europe. Eur J Health Econ. 2016;Suppl 1:1-5. doi: 10.1007/s10198-016-0780-7
  • Abt Sacks A, Perestelo-Pérez L, Rodriguez-Martin B, Cuellar-Pompa L, Algara Lopez M, Gonzalez Hernandez N, Serrano-Aguilar P. Breast cancer patients’narrative experiences about communication during the oncology care process: a qualitative study. Eur J Cancer Care (Engl.). 2016 Sep;25(5):719-33. doi: 10.1111/ecc.12384
  • Perestelo-Pérez L, Rivero Santana A, Boronat M, Sanchez-Afonso JA, Perez-Ramos JM, Montori VM, Serrano-Aguilar P. Effect of the statin choice encounter decision aid in Spanish patients with type 2 diabetes: A randomized trial. Patient Educ Couns. 2016 Feb;99(2):295-9. doi: 10.1016/j.pec.2015.08.032
  • Del Pino-Sedeño T, Trujillo-Martin MM, Ruiz-Irastorza G, Cuellar-Pompa L, de Pascual-Medina AM, Serrano-Aguilar P. Spanish Systemic Lupus Erythematosus CPG Development Group. Effectiveness of nonpharmacologic interventions for decreasing fatigue in adults with systemic lupus erythematosus: a systematic review. Arthritis Care Res (Hoboken). 2016 Jan;68(1):141-8. doi:10.1002/acr.22675
  • Vallejo-Torres L, Castilla I, Couce ML, Perez-Cerda C, Martin-Hernandez E, Pineda M, Campistol J, Arrospide A, Morris S, Serrano-Aguilar P. Cost-efectiveness analysis of a national newborn screening program for biotinidase deficiency. 2015 Aug;136(2):e424-32. doi: 10.1542/peds.2014-3399
  • Serrano-Aguilar P, Trujillo-Martin MM, Perez de la Rosa A, Cuellar-Pompa L, Saavedra-Medina H, Linertova R, Perestelo-Perez L, Perez-Ramos J, Rivero-Santana A. Patient participation in a Clinical Guideline Development for Systemic Lupus Erythematosus. Patient Education and Counseling. 2015 Sep;98(9):1156-63. doi: 10.1016/j.pec.2015.05.022
  • Vallejo-Torres L, Castilla I, Gonzalez N, Hunter R, Serrano-Perez P, Perestelo-Pérez L. Cost-effectiveness of electroconvulsive therapy compared to repetitive transcranial magnetic stimulation for treatment-resistant severe depression: a decision model. Psychol Med. 2015 May;45(7):1459-70. doi: 10.1017/S0033291714002554